You know, Gumball is one of the few current-day cartoons I not only don't mind watching with my kid relatives, but I can enjoy it on its own. At first I wasn't into it, but it grew on me and now I think it's hilarious. It has originality and with so much media (books, TV movies, music) being so cookie-cutter nowadays, Gumball's a refreshing dose of wacky originality.
And if anyone remembers Jetix back in the day (it's Disney XD now), W.I.T.C.H. was a surprisingly good show. I thought it would just be another ho-hum "non-Japanese trying to do magical girl anime, nobody can do that better than the Japanese, I am an immature weeaboo" but then I actually watched a few episodes and was like, "Damn, this show's actually pretty cool."
And I'll admit it, I had a brony phase. Massive guilty pleasure there. I phased out of that after season 4 (which I thought was awful) but I might still watch it once in a while... if/when no one's around. That's another show that, at least in the early going, turned out to be surprisingly solid. It was a couple buddies of mine who got me to watch it. I was all like, "Dude, My Little Pony?!?! What are you, a 6 year old girl?!?!?!" But then they pulled the Sailor Moon defense of "Well, Sailor Moon is made for the 6-12 year-old girl demographic and you like that." So I watched some and was like, "This isn't bad, it's not bad at all, it's rather good I'd say."
And my guilty pleasure comic books are Damsels in Excess and Zombie Tramp.