Yeah, the game is really forcing me down one path. It threw giant radscorpians at me right away when I went off the beaten path. Guess they want to funnel me down for the first few hours, but it's proving rather obnoxious at this point.
Also, the autosaving problem seems to be related to steamcloud. Great job, guys! Talk about how awesome stemcloud and Fallout are going to be together and then release the game without checking to make sure the damn thing works. This game stinks of being shoved out the door WAY too early. Between that, repeating dialogue, enemies trapped in walls, and shit that doesn't even make sense (killing convicts on one game gave me good karma, and before it was giving me nothing) this is proving to be quite the disappointing experience for me so far.