The PEC room is where it crashed. I knew I wasn't supposed to save in the Puzzle Rooms going in because of the glitch, but I didn't realise the PEC room was just seriously bugged in general. How frustrating.
I had a freeze in the PEC room, so I think you and I had the same problem (my freezes dealt with the item screen both times). However, PEC room's notoriety (and one other I forgot) comes from the fact that if you save there, your
(in other words, you're starting a new game).
Apparently Aksys is looking into it, but it might be too little too late by the time something is done.
Speaking of gaming fuck ups: Resident Evil 6 apparently has its own troubles when it comes to co-op difficulty; it takes the campaign leader's difficulty, but doesn't "share" it with whoever joins your game (so 1p can play on Hard, while 2p is stuck on Normal). There's a work around it, but I just wonder what about it was a good idea...
I feel a bit better about this though, seeing as how I was typically getting bruised and beaten down while Yodes was walking away scratch free -- I thought I sucked ass at the game.... :D