| Game | Platform | Developer | Publisher (JP) | Publisher (NA) | Publisher (PAL) |
|---|---|---|---|---|---|
| Shadowrun (Genesis) | Sega Genesis | BlueSky Software | N/A | SEGA | N/A |
| Shadowrun (SNES) | Super Nintendo Entertainment System | Beam Software | N/A | Data East | Laser Beam Entertainment |
| Shadowrun Chronicles: Boston Lockdown | Android, Linux, Microsoft Windows, Ouya, iOS, macOS | Cliffhanger Productions | N/A | Cliffhanger Productions | Cliffhanger Productions |
| Shadowrun Returns | Android, Linux, Microsoft Windows, iOS, macOS | Harebrained Schemes | N/A | Harebrained Schemes | Harebrained Schemes |
| Shadowrun Trilogy | Linux, Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S, Nintendo Switch, Sony PlayStation 4, Sony PlayStation 5, macOS | Codeglue, Harebrained Schemes | Paradox Interactive | Paradox Interactive | Paradox Interactive |
| Shadowrun: Dragonfall – Director’s Cut | Linux, Microsoft Windows, macOS | Harebrained Holdings | N/A | Harebrained Schemes | Harebrained Schemes |
| Shadowrun: Dragonfall DLC | Linux, Microsoft Windows, macOS | Harebrained Schemes | N/A | Harebrained Schemes | Harebrained Schemes |
| Shadowrun: Hong Kong | Linux, Microsoft Windows, macOS | Harebrained Schemes | N/A | Harebrained Schemes | Harebrained Schemes |
| Shadows of Adam | Linux, Microsoft Windows, Nintendo Switch, macOS | Something Classic Games | N/A | Something Classic Games | Something Classic Games |
| Shadows Over Loathing | Linux, Microsoft Windows, Nintendo Switch, macOS | Asymmetric | N/A | Asymmetric | Asymmetric |
| Shadows: Awakening | Microsoft Windows, Microsoft Xbox One, Sony PlayStation 4 | Games Farm | N/A | Kalypso Media | Kalypso Media |
| Shadows: Heretic Kingdoms | Microsoft Windows | Games Farm | N/A | bitComposer Games | bitComposer Games |
| Shardlight | Microsoft Windows, iOS | Wadjet Eye Games | N/A | Wadjet Eye Games | Wadjet Eye Games |
| Shattered – Tale of the Forgotten King | Microsoft Windows | Redlock Studio | N/A | Redlock Studio | Redlock Studio |
| Shattered Galaxy | Microsoft Windows | Nexon | N/A | Nexon, Tri Synergy | Nexon, Tri Synergy |
| Shattered Heaven | Microsoft Windows | Leonardo Production | N/A | Leonardo Interactive | Leonardo Interactive |
| Shattered Planet | Android, Microsoft Windows, iOS, macOS | Kitfox Games | N/A | Kitfox Games | Kitfox Games |
| Shattering Obsidian | |||||
| She Dreams Elsewhere | Linux, Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S, Nintendo Switch, macOS | Studio Zevere | N/A | Studio Zevere | Studio Zevere |
| Shenmue | Sega Dreamcast | SEGA | SEGA | SEGA | SEGA |
| Shenmue I & II | Microsoft Windows, Microsoft Xbox One, Sony PlayStation 4 | SEGA | SEGA | SEGA | SEGA |
| Shenmue II | Microsoft Xbox, Sega Dreamcast | SEGA | SEGA | SEGA | SEGA |
| Shenmue III | Microsoft Windows, Sony PlayStation 4 | Neilo, Ys Net | Deep Silver | Deep Silver | Deep Silver |
| Shenmue III Enhanced | Microsoft Windows, Microsoft Xbox Series X|S, Sony PlayStation 5 | Ys Net | N/A | ININ Games | ININ Games |
| Shenmue Online [Cancelled] | Microsoft Windows, macOS | SEGA | N/A | N/A | N/A |
