| Game | Platform | Developer | Publisher (JP) | Publisher (NA) | Publisher (PAL) |
|---|---|---|---|---|---|
| SINoALICE | Android, iOS | Pokelabo | Square Enix | Pokelabo | Pokelabo |
| SKALD: Against the Black Priory | Microsoft Windows, macOS | High North Studios | N/A | Raw Fury | Raw Fury |
| Skellboy | Linux, Microsoft Windows, Microsoft Xbox One, Nintendo Switch, Sony PlayStation 4, macOS | Umaiki Games | N/A | Fabraz | Fabraz |
| Skies of Arcadia | Sega Dreamcast | Overworks | SEGA | SEGA | SEGA |
| Skies of Arcadia Legends | Nintendo GameCube | Overworks | SEGA | SEGA | SEGA |
| Sky Oceans: Wings for Hire | Microsoft Windows, Microsoft Xbox Series X|S, Nintendo Switch, Sony PlayStation 5 | Octeto Studios | PQube | PQube | PQube |
| Skyborn | Linux, Microsoft Windows, macOS | Dancing Dragon Games | N/A | Degica | Degica |
| Skyforge | Microsoft Windows | Allods Team, Obsidian Entertainment | N/A | My.com | My.com |
| Skyhill | Android, Linux, Microsoft Windows, Microsoft Xbox One, Nintendo Switch, Sony PlayStation 4, iOS, macOS | Mandragora Team | N/A | Daedalic Entertainment | Daedalic Entertainment |
| Skyshine’s BEDLAM | Microsoft Windows, macOS | Skyshine Games | N/A | Versus Evil | Versus Evil |
| Slay the Princess | Linux, Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S, Nintendo Switch, Sony PlayStation 4, Sony PlayStation 5, macOS | Black Tabby Games | N/A | Black Tabby Games | Black Tabby Games |
| Slay the Spire 2 | Linux, Microsoft Windows, macOS | Mega Crit | Mega Crit | Mega Crit | Mega Crit |
| Slayers Royal 2 | Sega Saturn, Sony PlayStation | Onion Egg | ESP Software, Kadokawa Games | N/A | N/A |
| Slayers Wonderful | Sony PlayStation | Banpresto | Banpresto | N/A | N/A |
| Slime Heroes | Microsoft Windows, Microsoft Xbox Series X|S, Nintendo Switch, Sony PlayStation 4, Sony PlayStation 5 | Pancake Games | N/A | Whitethorn Games | Whitethorn Games |
| Slimes | Microsoft Windows | scitydreamer | N/A | scitydreamer | scitydreamer |
| Small Saga | Microsoft Windows | Darya Noghani | N/A | Darya Noghani | Darya Noghani |
| Smoke and Sacrifice | Microsoft Windows, Microsoft Xbox One, Nintendo Switch, Sony PlayStation 4 | Solar Sail Games | N/A | Curve Games | Curve Games |
| Snack World: The Dungeon Crawl – Gold | Nintendo Switch | Level-5, h.a.n.d. | Level-5 | Level-5 | Level-5 |
| Snacko | Microsoft Windows, Nintendo Switch, Sony PlayStation 4, Sony PlayStation 5 | Bluecurse Studios | N/A | Armor Games Studios | Armor Games Studios |
| Snatcher | MSX2, Sega CD, Sega Saturn, Sony PlayStation, TurboGrafx-16 | Konami | Konami | Konami | Konami |
| Soccer Story | Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S, Sony PlayStation 4, Sony PlayStation 5 | PanicBarn | N/A | No More Robots | No More Robots |
| Sol 705 | Land Patricio - Space Indie Studios | Land Patricio - Space Indie Studios | |||
| Sol Trigger | Sony PSP | Imageepoch | Imageepoch | N/A | N/A |
| Solace State | Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S | Vivid Foundry | N/A | Vivid Foundry | Vivid Foundry |
