| Game | Platform | Developer | Publisher (JP) | Publisher (NA) | Publisher (PAL) |
|---|---|---|---|---|---|
| Story of Seasons: Pioneers of Olive Town | Microsoft Windows, Nintendo Switch, Sony PlayStation 4 | Marvelous Entertainment | Marvelous Entertainment | XSEED Games | Marvelous Entertainment |
| Story of Seasons: The Tale of Two Towns+ | Nintendo 3DS | Marvelous Entertainment | Marvelous Entertainment | N/A | N/A |
| Story of Seasons: Trio of Towns | Nintendo 3DS | Marvelous Entertainment | Marvelous Entertainment | Marvelous Entertainment | Nintendo |
| Storyteller | Microsoft Windows, Nintendo Switch, macOS | Daniel Benmergui | Annapurna Interactive | Annapurna Interactive | Annapurna Interactive |
| Stranger of Paradise Final Fantasy Origin | Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S, Sony PlayStation 4, Sony PlayStation 5 | Square Enix, Team Ninja | Square Enix | Square Enix | Square Enix |
| Stranger of Sword City | Microsoft Windows, Microsoft Xbox 360, Microsoft Xbox One, Sony PS Vita | Experience | Mages | NIS America | NIS America |
| Stranger Than Heaven | Ryu Ga Gotoku Studio | SEGA | SEGA | SEGA | |
| Stray Blade | Microsoft Windows, Microsoft Xbox Series X|S, Sony PlayStation 5 | Point Blank Games | 505 Games | 505 Games | 505 Games |
| Stray Children | Microsoft Windows, Nintendo Switch | Onion Games | Onion Games | Onion Games | Onion Games |
| Stray Gods: The Roleplaying Musical | Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S, Nintendo Switch, Sony PlayStation 4, Sony PlayStation 5 | Summerfall Studios | Humble Games | Humble Games | Humble Games |
| Street Fighter: Duel | Android, iOS | Tencent Games, Topjoy | A Plus | A Plus, Crunchyroll Games | A Plus, Crunchyroll Games |
| Streets of Kamurocho | Microsoft Windows | Empty Clip Studios, SEGA | SEGA | SEGA | SEGA |
| Strife | MS-DOS | Rogue Entertainment | N/A | Velocity | Studio 3DO |
| Strife: Veteran Edition | Linux, Microsoft Windows, macOS | Nightdive Studios, Rogue Entertainment | N/A | Nightdive Studios | Nightdive Studios |
| Strike Team Gladius | Microsoft Windows | N/A | Wave Light Games | Wave Light Games | |
| Strong Bad’s Cool Game for Attractive People | Microsoft Windows, Nintendo Wii, Sony PlayStation 3, macOS | Telltale Games | N/A | Telltale Games | Telltale Games |
| Strugarden | Microsoft Windows | FromNetworks | Sammy | N/A | N/A |
| Struggle for Talyria | Microsoft Windows | Scalding Soup Studios | N/A | Scalding Soup Studios | Scalding Soup Studios |
| Stupid Invaders | Microsoft Windows, Sega Dreamcast, macOS | Xilam | N/A | Ubisoft | Ubisoft |
| Sudeki | Microsoft Windows, Microsoft Xbox | Climax Studios | N/A | Xbox Game Studios | Xbox Game Studios |
| Suhoshin | Microsoft Windows | No More 500 | N/A | No More 500 | No More 500 |
| Suigetsu ~Lost Heart~ | Sega Dreamcast | F&C - FC01 | KID | N/A | N/A |
| Suikoden | Microsoft Windows, Mobile, Sega Saturn, Sony PS Vita, Sony PlayStation, Sony PlayStation 3 | Konami | Konami | Konami | Konami |
| Suikoden I & II | Sony PSP | Konami | Konami | N/A | N/A |
| Suikoden I & II HD Remaster: Gate Rune and Dunan Unification Wars | Microsoft Windows, Microsoft Xbox One, Nintendo Switch, Sony PlayStation 4, Sony PlayStation 5 | Konami | Konami | Konami | Konami |
