| Game | Platform | Developer | Publisher (JP) | Publisher (NA) | Publisher (PAL) |
|---|---|---|---|---|---|
| Syberia II | Android, Microsoft Windows, Microsoft Xbox, Microsoft Xbox 360, Nintendo DS, Nintendo Switch, Sony PlayStation 2, Sony PlayStation 3, Windows Mobile, iOS, macOS | Microids | N/A | Microids | Microids |
| Syberia Remastered | Microsoft Windows, Microsoft Xbox Series X|S, Sony PlayStation 5 | Microids, Virtuallyz Gaming | N/A | Microids | Microids |
| Syberia: The World Before | Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S, Nintendo Switch, Sony PlayStation 4, Sony PlayStation 5 | Koalabs | Microids | Microids | Microids |
| Sylia | Microsoft Windows | Ensorcelled | N/A | Aldorlea Games | Aldorlea Games |
| Sympathy Kiss | Nintendo Switch | Otomate | Idea Factory | Idea Factory | Idea Factory |
| Symphonic Rain | Microsoft Windows | Kogado Studio | KOGADO STUDIO | Degica | Degica |
| Symphony of Eternity | Android, iOS | KEMCO | KEMCO | KEMCO | N/A |
| Symphony of the Origin | Android, iOS | KEMCO | KEMCO | KEMCO | N/A |
| Symphony of War: The Nephilim Saga | Microsoft Windows | Dancing Dragon Games | N/A | indie.io | indie.io |
| Syndream | Microsoft Windows | Ugono Studios | Ugono Studios | N/A | N/A |
| Synergia | Linux, Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S, Nintendo Switch, Sony PS Vita, Sony PlayStation 4, Sony PlayStation 5, macOS | Radi Art | Top Hat Studios | Top Hat Studios | Top Hat Studios |
| System Shock | MS-DOS, Microsoft Windows, macOS | Looking Glass Studios | N/A | Origin Systems | Origin Systems |
| System Shock (Remake) | Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S, Nintendo Switch, Nintendo Switch 2, Sony PlayStation 4, Sony PlayStation 5 | Nightdive Studios | N/A | Prime Matter | Prime Matter |
| System Shock 2 | Linux, Microsoft Windows, macOS | Irrational Games, Looking Glass Studios | N/A | Electronic Arts | Electronic Arts |
| System Shock 2: 25th Anniversary Remaster | Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S, Nintendo Switch, Sony PlayStation 4, Sony PlayStation 5 | Irrational Games, Looking Glass Studios, Nightdive Studios | N/A | Nightdive Studios | Nightdive Studios |
| Table of Tales: The Crooked Crown | Microsoft Windows, Nintendo Switch, Sony PlayStation 4 | Tin Man Games | N/A | Tin Man Games | Tin Man Games |
| Tabula Rasa | Microsoft Windows | Destination Games | N/A | NCSoft | NCSoft |
| Tachyon Dreams Anthology | Microsoft Windows | Cosmic Void | N/A | Cosmic Void | Cosmic Void |
| Tacoma | Microsoft Windows, Microsoft Xbox One, Sony PlayStation 4, macOS | Fullbright | Fullbright | Fullbright | Fullbright |
| Tactical Breach Wizards | Microsoft Windows | Suspicious Developments Inc | N/A | Suspicious Developments | Suspicious Developments |
| Tactics Ogre: Let Us Cling Together | Nintendo 3DS, Nintendo Wii, Nintendo Wii U, Sega Saturn, Sony PlayStation, Super Nintendo Entertainment System | Quest | Quest | Square Enix | N/A |
| Tactics Ogre: Let Us Cling Together (PSP) | Sony PSP | Quest, Square Enix | Square Enix | Square Enix | Square Enix |
| Tactics Ogre: Reborn | Microsoft Windows, Nintendo Switch, Sony PlayStation 4, Sony PlayStation 5 | Square Enix | Square Enix | Square Enix | Square Enix |
| Tactics Ogre: The Knight of Lodis | Nintendo Game Boy Advance | Quest | Nintendo | Atlus | N/A |
| Tactics Returners | Microsoft Windows | Triple Tech Arts | N/A | Triple Tech Arts | Triple Tech Arts |
