| Game | Platform | Developer | Publisher (JP) | Publisher (NA) | Publisher (PAL) |
|---|---|---|---|---|---|
| Soul of the Ultimate Nation | Microsoft Windows | Webzen | GameOn | NHN Corporation | Webzen |
| Soul Sacrifice | Sony PS Vita | Comcept, Marvelous Entertainment | Sony Interactive Entertainment | Sony Interactive Entertainment | Sony Interactive Entertainment |
| Soul Sacrifice Delta | Sony PS Vita | Comcept, Marvelous Entertainment | Sony Interactive Entertainment | Sony Interactive Entertainment | Sony Interactive Entertainment |
| Soul Tamer Kiki | Android, iOS | Minoraxis | N/A | Minoraxis | N/A |
| Soulbringer | Microsoft Windows | Gremlin Interactive, Infogrames | N/A | Interplay Entertainment | Interplay Entertainment |
| Souls of Chronos | Microsoft Windows, Nintendo Switch, Sony PlayStation 5 | FUTU Studio | Astrolabe Games | Astrolabe Games | Astrolabe Games |
| Soulstice | Microsoft Windows, Microsoft Xbox Series X|S, Sony PlayStation 5 | Reply Game Studios | Modus Games | Modus Games | Modus Games |
| Soulvars | Android, Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S, Nintendo Switch, Sony PlayStation 4, Sony PlayStation 5, iOS | ginolabo | Shueisha Games | Shueisha Games | Shueisha Games |
| Sound of Drop – fall into poison – | Microsoft Windows | aiueoKompany | Entuziasty Team, Kawa Soft, Sekai Project, aiueoKompany | Sekai Project | Sekai Project |
| South of the Circle | Apple Arcade, Microsoft Windows, Microsoft Xbox One, Microsoft Xbox Series X|S, Nintendo Switch, Sony PlayStation 4, Sony PlayStation 5 | State of Play | 11 bit studios | 11 bit studios | 11 bit studios |
| South Park: The Fractured but Whole | Microsoft Windows, Microsoft Xbox One, Nintendo Switch, Sony PlayStation 4 | Ubisoft | N/A | Ubisoft | Ubisoft |
| South Park: The Stick of Truth | Microsoft Windows, Microsoft Xbox 360, Microsoft Xbox One, Nintendo Switch, Sony PlayStation 3, Sony PlayStation 4 | Obsidian Entertainment | N/A | Ubisoft | Ubisoft |
| Sovereign Syndicate | Microsoft Windows | Crimson Herring Studios | N/A | Crimson Herring Studios | Crimson Herring Studios |
| Sovereign Tea | Microsoft Windows | 3 Halves Games | N/A | 3 Halves Games | 3 Halves Games |
| Space Funeral | Microsoft Windows | thecatamites | N/A | thecatamites | thecatamites |
| Space Punks | Microsoft Windows | N/A | Flying Wild Hog | Flying Wild Hog | |
| Space Wreck | Microsoft Windows | Pahris Entertainment | N/A | Pahris Entertainment | Pahris Entertainment |
| Spaceman Memories | Linux, Microsoft Windows | NerdyPunkDev | NerdyPunkDev | NerdyPunkDev | NerdyPunkDev |
| Sparklite | Microsoft Windows, Microsoft Xbox One, Nintendo Switch, Sony PlayStation 4 | Red Blue Games | N/A | Merge Games | Merge Games |
| Spear Song | Microsoft Windows | Divovision Games | N/A | Divovision Games | Divovision Games |
| Spectral Force | Sony PlayStation, Sony PlayStation 3 | Idea Factory | Idea Factory | N/A | N/A |
| Spectral Force 2 | Sony PSP, Sony PlayStation, Sony PlayStation 3 | Idea Factory | Idea Factory | N/A | N/A |
| Spectral Force 3 | Microsoft Xbox 360 | Idea Factory | Idea Factory | Atlus | N/A |
| Spectral Force Chronicle | Sony PlayStation 2 | Idea Factory, Neverland | Idea Factory | N/A | N/A |
| Spectral Force Genesis | Nintendo DS | Idea Factory | Idea Factory | Ignition Entertainment | N/A |
